Comparison of SARS-CoV-2 Variants of Concern 202012/01 (U.K. Variant) and D614G Variant Transmission by Different Routes in Syrian Hamsters

Introduction: Many SARS-CoV-2 variants of concern (VOC) have been reported recently that were linked to increased transmission. In our earlier study using VOC 202012/01 (U.K. variant) and D614G variant in the hamster model, we observed higher viral RNA shedding through nasal wash case U.K. with lower pathogenicity lung. this study, studied transmission these two by direct contact, aerosol, fomite routes Syrian hamsters compared load body weight changes exposed both understand efficiency. Methods: Nasal, throat, rectal swabs collected sequentially assess till 14 days. Results: Transmission could be established direct, contact hamsters. Body loss or animals did not show any statistical significance. Conclusion: The demonstrated comparable given conditions. Provided data, it seems all exposure are effective leading